How to read the plotter
Explore how amounts and timing change a curve. The model label tells you what the vertical axis means; the curve does not predict how strong an effect will feel.
Three kinds of curve
Published reference
Concentration in the stated blood unit
Uses a published model with a fixed product, route and study population. Changing the schedule changes the example, not the reference person.
Examples: Semaglutide Injection (Ozempic/Wegovy), Semaglutide Oral (Rybelsus), Tirzepatide (Mounjaro), SS-31 (Elamipretide) …
Estimated concentration
Concentration estimated from source data
Reconstructs a curve from study endpoints or label parameters. Some peaks are measured; others are derived. Model details identify the calibration and the parts that remain approximate.
Examples: HCG, Human Growth Hormone (HGH), Retatrutide, Mazdutide …
Relative timing
Relative units, not blood concentration
Useful for comparing amounts and schedules when an absolute concentration cannot be established. Its timing may come from a study, a different route or species, or an explicit assumption.
Examples: 5-Amino-1MQ, Adipotide, HGH Fragment 176-191 (AOD-9604), MGF (Mechano Growth Factor) …
What comparisons tell you
- Same compound, different amounts. Compare curve height and timing within the same model. Linear dose scaling is a mathematical assumption, and may become less accurate outside the studied range.
- Same total, different schedules. With accumulation on, overlapping doses add together. Changing their spacing can change the peaks and dips.
- Different compounds or outputs. Different relative scales and concentration endpoints are normalized to each curve’s own peak. This compares shape, not potency, combined effect or equivalent doses.
- Injected testosterone. The curve includes the entered doses only. The body’s own production is excluded, so this is not a total-testosterone blood test.
Where the numbers come from
Open Model details beside a curve for its product, route, population, timing basis and sources. A measured value from one setting may not transfer to another. The half-life reference keeps those timing notes attached to each entry.
When a defensible absolute calibration is missing, the plotter uses an explicitly relative scale. It does not substitute an arbitrary peak and label it ng/mL or another blood unit. Catalog entries without a usable model remain informational.
Calculation details
Published reference models use one or two compartments with absorption. Some include a source-defined delay before absorption begins. Apparent clearance and volumes already account for bioavailability; it is not applied twice.
Endpoint estimates reconstruct the curve from the declared calibration dose, peak, peak timing and terminal rate. A derived calibration peak is identified as calculated. Matching these inputs does not guarantee the same total exposure or full time course as the source study.
A relative model uses declared absorption and terminal timing assumptions. One fixed reference amount has a single-dose peak of 1 relative unit; other amounts scale proportionally. That reference is independent of the example dose initially shown in the controls.
Accumulation adds every dose’s contribution. With accumulation off, the curve shows the largest single-dose contribution at each time instead. The adjustment slider scales the result; it does not calibrate it to laboratory measurements.
Saved dates and calendar entries determine when doses enter the calculation. hCG activity is entered in IU; its legacy stored numbers are preserved for compatibility and are not a physical conversion to milligrams.
Scope of the checks
Source review checks units, formulation, route, population and calibration. Numerical checks compare the calculations with published parameters and independently calculated examples. These checks are not clinical validation of predictions for a visitor.
Individual absorption, metabolism, natural hormone production and treatment response can differ. Use the curves to understand assumptions and comparisons, not to select a personal treatment or dose.